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  3. Oral Prebiotics: What They Are and Why You Need Them

Oral Prebiotics: What They Are and Why You Need Them

By Gerry Curatola | Aug 18, 2025
Oral Prebiotics

Your mouth is a delicate ecosystem of good and bad bacteria, and maintaining that balance is important for strong teeth, fresh breath, and overall oral wellness. Oral prebiotics support this balance by feeding beneficial bacteria so they can fight off harmful microbes. 

Prebiotic toothpastes like Revitin enhance daily oral care by reducing harmful bacteria and supporting a healthier microbiome.  

What Are the Benefits?

Oral prebiotics support a healthy balance of bacteria in your mouth, working with your body’s natural defenses for a stronger, fresher smile. Here’s how adding them to your routine can make a real difference.

A Balanced Oral Microbiome

Oral prebiotics act like fuel for the beneficial bacteria already living in your mouth. These friendly microbes are your body’s natural defense system, working to keep harmful bacteria under control. By feeding and strengthening them, prebiotics help maintain a balanced oral microbiome, which is important for long-term oral health. [1]

A healthy microbiome creates a more resilient environment against common dental problems — with consistent use, oral prebiotics can keep this balance steady. [2] An imbalance, or dysbiosis, can lead to bad breath, cavities, gum disease, and inflammation.

Freshen Breath Naturally

Bad breath, or halitosis, often comes from an overgrowth of harmful bacteria that produce foul-smelling sulfur compounds. [3] Oral prebiotics target the root of the problem by nourishing the good bacteria that crowd out the odor-causing ones.

Unlike mouthwashes that may kill all bacteria, good and bad, prebiotics encourage a thriving community of healthy microbes for naturally fresh breath. They don’t just mask bad breath with artificial flavors or harsh chemicals.

Reduce Risk of Gingivitis

Gingivitis is the earliest stage of gum disease, caused by harmful bacteria that irritate and inflame the gums. Oral prebiotics help fight back at those early stages by giving good bacteria the nourishment they need to multiply and defend your gums. 

These beneficial microbes naturally compete with harmful bacteria, reducing their ability to stick to the gum line and cause inflammation. [4] Supporting your oral microbiome in this way makes it harder for gingivitis to take hold, helping to prevent bleeding gums, swelling, and discomfort. 

Help Prevent Cavities

When harmful bacteria feed on sugars and produce acids that erode your tooth enamel, cavities form. By strengthening levels of good bacteria in your mouth, oral prebiotics make it harder for cavity-causing bacteria to thrive. [5] With fewer acid attacks and threats of erosion, your enamel stays stronger and more resilient. 

This natural oral health solution has fewer side effects than traditional treatments, like fluoride. Oral prebiotics may not directly strengthen enamel, but they naturally reduce acid-producing bacteria that cause cavities — supporting a more holistic, long-term approach.

Limit Plaque Buildup

Plaque is a sticky film of bacteria that forms on your teeth and gums. It can turn into tartar and lead to serious dental problems if left unchecked. Oral prebiotics help reduce plaque by boosting the good bacteria that naturally control plaque-forming microbes. [6]

When your microbiome is balanced, harmful bacteria have a harder time sticking to teeth and multiplying. This makes your mouth feel cleaner and supports long-term dental health by reducing the risk of gum disease and tooth decay. 

When paired with natural toothpaste ingredients like calcium carbonate — a gentler polish that removes surface plaque — prebiotics can help reduce the risk of oral health issues down the line.

Why a Balanced Oral Microbiome Matters

Your oral cavity is home to billions of good and bad bacteria that make up your oral microbiome. [7] When balanced, the good bacteria act as natural defenders to help control harmful microbes that cause bad breath, cavities, and gum disease. 

When poor diet, stress, or harsh oral products disrupt this balance, harmful bacteria can take over, leading to plaque buildup, inflammation, and decay. Supporting the good bacteria helps protect your teeth and gums, keeping your mouth healthy and resilient. 

This balance is part of the sialo-microbial-dental complex, linking saliva, oral bacteria, and teeth. Knowing how this works can help you understand why prebiotics are so important for your oral health.

A balanced oral microbiome isn’t just important for a bright smile, though. Gum disease contributes to serious conditions like heart disease, diabetes, and respiratory infections. [8] Harmful oral bacteria can enter the bloodstream, triggering systemic inflammation. [9] 

Maintaining a healthy oral microbiome helps keep these risks low, supporting dental health, the immune system, and overall well-being.

Prebiotics vs. Probiotics

Prebiotics are natural compounds that feed the good bacteria in your gut and mouth, helping them grow and thrive. Probiotics are live beneficial bacteria you can introduce through probiotic supplements or fermented foods. [10] Prebiotics and probiotics work together in gut and oral health to maintain a balanced microbiome. 

While probiotics add helpful bacteria, prebiotics provide the nourishment these bacteria need to flourish. One isn’t better than the other. 

Together, they:

  • Support immune function

  • Strengthen oral defenses 

  • Promote a healthy environment where good microbes outcompete harmful ones

  • Contribute to optimal whole-body wellness

Note: Probiotics even come in the form of dental probiotic lozenges for an improved oral microbiome!

Revitin: The Original Prebiotic Toothpaste

Revitin is the result of 30 years of research into the mouth’s natural ecology. Designed to nurture a healthier oral microbiome with the power of natural prebiotics that include:

  • Chondrus crispus: Rich in natural polysaccharides, this red seaweed nourishes beneficial oral bacteria. It also acts as a natural alternative to chemical thickeners, creating a smooth texture.

  • Cranberry seed oil: This ingredient is a powerful combo of essential fatty acids, antioxidants, and prebiotic compounds. It provides a better environment for good bacteria to thrive.

  • Stevia leaf extract: Non-GMO stevia provides nutrients and minerals that help feed the good bacteria in your mouth. This reduces the buildup of harmful plaque and keeps your mouth balanced, with fewer side effects than sugar alcohols like xylitol.

  • Xantham gum: This soluble fiber is the result of a probiotic fermentation process. It is a prebiotic substrate for healthy bacterial flora and a more balanced oral environment. 

This natural toothpaste combines prebiotic benefits with ingredients specifically chosen to support holistic oral wellness and dentistry. These include:

  • Antioxidants (Vitamin C & E)
    — Support gum health
    — Help form a barrier against oxidative stress

  • Anti-inflammatory enzymes (Coenzyme Q10 / CoQ10)
    — Promote healthy gum tissue repair

  • Natural essential oils (like spearmint)
    — Act as gentle antimicrobials to reduce harmful bacteria
    — Help combat bad breath and plaque formation
    — Maintain a healthy balance of good oral bacteria

Free from harsh chemicals and artificial additives, Revitin offers a cleaner, healthier way to care for your oral microbiome.

Try Revitin Today

How Oral Health Affects Whole-Body Health

The health of your mouth and oral microbiome is deeply connected to overall wellness, especially when you look at the mouth-gut connection. 

The bacteria in your mouth can influence your gut microbiome, affecting:

  • Digestion

  • Nutrient absorption

  • Immune system 

When harmful pathogens thrive, they can travel beyond your mouth and cause inflammation, digestive issues, and systemic health problems.

Prebiotics support this mouth-body connection by:

  • Nourishing beneficial bacteria

  • Protecting teeth and gums

  • Support smoother digestion

  • Reducing inflammation

Dr. Gerry Curatola explores this idea in his book, The Mouth-Body Connection, which includes tips on supporting your oral and overall wellness. Caring for your oral microbiome is one of the most powerful steps for lifelong health.

Take Steps Toward a Healthier Mouth 

Your journey to better oral health starts with simple but powerful choices. Revitin is the original prebiotic toothpaste that helps nourish the good bacteria in your mouth for a cleaner, healthier smile. 

Pair that with smart daily habits:

  • Skip harsh, alcohol-based mouthwashes that strip away helpful microbes. 

  • Add more prebiotic- and inulin-rich fructooligosaccharides (FOS) like apples, chicory root, onions, and asparagus to your diet. 

  • Brush and floss regularly for solid oral hygiene. 

With the right care, you can create a balanced oral microbiome that supports your teeth, gums, and overall health.

Sources

  1. Luo, S.C., Wei, S.M., Luo, X.T., et al. (2024). How probiotics, prebiotics, synbiotics, and postbiotics prevent dental caries: an oral microbiota perspective. NPJ Biofilms Microbiomes, 10(1), 14. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC10894247/

  2. Rajasekaran, J.J., Krishnamurthy, H.K., Bosco, J., et al. (2024). Oral microbiome: A review of its impact on oral and systemic health. Microorganisms, 12(9), 1797. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC11434369/

  3. Hampelska, K., Jaworska, M.M., Babalska, ZŁ., et al. (2020). The role of oral microbiota in intra-oral halitosis. Journal of Clinical Medicine, 9(8), 2484. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC7465478/

  4. Doucette, H., Ward, R., Wheeldon, C., et al. (2024). The impact of prebiotics and probiotics on the oral microbiome of individuals with periodontal disease: a scoping review. The Canadian Journal of Dental Hygiene, 58(3), 182-195. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC11539943/

  5. Inchingolo, A.D., Malcangi, G., Semjonova, A., et al. (2022). Oralbiotica/oralbiotics: the impact of oral microbiota on dental health and demineralization: a systematic review of the literature. Children (Basel), 9(7), 1014. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC9323959/

  6. Havsed, K., Stensson, M., Jansson, H., et al. (2021). Bacterial composition and metabolomics of dental plaque from adolescents. Frontiers in Cellular and Infection Microbiology, 11, 716493.Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC8362896/

  7. Krishnan, K., Chen, T., & Paster, B. J. (2017). A practical guide to the oral microbiome and its relation to health and disease. Oral Diseases, 23(3), 276-286. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC5122475/

  8. Martínez-García, M. &Hernández-Lemus, E. (2021). Periodontal inflammation and systemic diseases: an overview. Frontiers in Physiology, 12, 709438. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC8578868/

  9. Li, X., Kolltveit, K.M., Tronstad, L., et al. (2000). Systemic diseases caused by oral infection. Clinical Microbiology Reviews, 13(4), 547-558. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC88948/

  10. Pyo, Y., Kwon, K.H., & Jung, Y.J. (2024). Probiotic functions in fermented foods: anti-viral, immunomodulatory, and anti-cancer benefits. Foods, 13(15), 2386. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC11311591/

  11. Squarzanti, D.F., Dell'Atti, F., Scalia, A.C., et al. (2024). Exploring the in vitro antibacterial potential of specific probiotic strains against oral pathogens. Microorganisms, 12(3), 441. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC10972368/

  12. Naureen, Z., Medori, M.C., Dhuli, K., et al. (2022). Polyphenols and lactobacillus reuteri in oral health. Journal of Preventive Medicine and Hygiene, 63(2 Suppl 3), E246-E254. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC9710395/

  13. Guo, M., Wu, J., Hung, W., et al. (2023). Lactobacillus paracasei ET-22 suppresses dental caries by regulating microbiota of dental plaques and inhibiting biofilm formation. Nutrients, 15(15), 3316. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC10421449/

  14. Ehrhardt, S., Guo, N., Hinz, R., et al. (2016). Saccharomyces boulardii to prevent antibiotic-associated diarrhea: a randomized, double-masked, placebo-controlled trial. Open Forum Infectious Diseases, 3(1), ofw011. Full text: https://pmc.ncbi.nlm.nih.gov/articles/PMC4785405/

 

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